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Find answers to common questions about VIJOICE and PROS
VIJOICE is a prescription medicine used to treat adults and children 2 years of age and older with severe phosphatidylinositol-3-kinase catalytic subunit alpha (PIK3CA)-Related Overgrowth Spectrum (PROS).
It is not known if VIJOICE is safe and effective in children younger than 2 years of age.
Learn more about VIJOICE here.
In a real-world study of 57 people living with PIK3CA-Related Overgrowth Spectrum, or PROS, VIJOICE reduced the size of overgrowths and improved PROS symptoms. There were also improvements in functioning for daily activities.
Learn more about the safety and efficacy of VIJOICE here.
VIJOICE targets the underlying cause of PIK3CA-Related Overgrowth Spectrum, or PROS. VIJOICE blocks the defective PI3Kα protein that gets made by an abnormal PIK3CA gene. A mutation (abnormal change) to this gene is the underlying cause of PROS. VIJOICE can also unintentionally affect healthy cells.
VIJOICE is a once-daily tablet or tablets that should be taken by mouth, with food, and at the same time each day. For people who are unable to swallow tablets, VIJOICE can be crushed and made into a mixture with water.
Find step-by-step instructions here.
As with any medication, you may experience side effects while taking VIJOICE. Some of the most common adverse reactions are high blood sugar, mouth sores, and diarrhea. Click here to learn more about potential side effects.
VIJOICE targets your child’s abnormal overgrowths, not their natural growth as they age.
In a longer-term study with VIJOICE that evaluated safety and efficacy, most children (29/38) were within standard, 5th to 95th, height and weight percentiles over time.
PROS stands for PIK3CA-Related Overgrowth Spectrum. PROS is the name for a group of approximately 13 different medical conditions that are caused by a mutation in a gene called PIK3CA. The term mutation means that there is an abnormal change or alteration in that gene.
In 2013, researchers proposed grouping abnormal growth, vascular conditions, and lymphatic conditions caused by PIK3CA mutations under the term PROS. By uniting these various conditions under one new term, researchers hoped to improve diagnosis, help manage symptoms, and establish future clinical trials.
A PIK3CA mutation is an abnormal change to a specific part of your DNA that is called the PIK3CA gene. This change is what causes PIK3CA-Related Overgrowth Spectrum, or PROS, conditions.
Discover the link between a PIK3CA mutation and your PROS condition here.
Is VIJOICE right for me?
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Downloadable Resources
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